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Second, radiation can indirectly induce endothelial cells to secrete TNF-, interleukin (IL)-1 and other cytokines to activate the NF-B pathway, leading to inflammatory infiltration, thus damaging the vascular endothelium and aggravating RE 41

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However, current evidence supporting AOX in improving important reproductive outcomes such as LBR remains low, necessitating further studies

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J Neurosci Res (2020) 98(11):235769

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FDA labeling advises renal-function monitoring when adverse reactions could lead to volume depletion, especially during treatment initiation or dose escalation

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S2CID 24730915

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